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Abstract This study aims to analyze the level of disability in printing PT. Padang Graindo Mediatama which focuses on producing newspapers using the six sigma method. The analytical tools used in this study include check sheets, P-charts, fishbone, and pareto diagrams. Six sigma steps are define, measure, analyze and improve. This research is expected to be able to improve the quality of prosducts based on zero defects or 3.4 disabilities per million opportunities by reducing the number of defects in the printing process. From the results of the analysis and research that has been done it turns out that there are still products that are blurry or opaque at 4.4%. Based on the chart of the control chart it is known that there are six (6) points that are outside the control boundary which indicate that there are still high deviations in the production process. The number of defective products in PT. Padang Graindo Mediatama is at the sigma level of 3.21 with DPMO of 43,959 copies and it is known that factors that influence product quality include machinery, people, materials and methods. Keywords : Quality Control, Six Sigma, DPMO